{"id":5690,"date":"2022-12-01T07:01:38","date_gmt":"2022-12-01T07:01:38","guid":{"rendered":"https:\/\/qualitywebbiz.com\/newsunridge\/?page_id=5690"},"modified":"2023-03-28T18:38:07","modified_gmt":"2023-03-29T01:38:07","slug":"mixed-connective-tissue-disease","status":"publish","type":"page","link":"https:\/\/sunridgemedical.com\/conditions\/autoimmune-diseases\/mixed-connective-tissue-disease\/","title":{"rendered":"Mixed Connective Tissue Disease"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"5690\" class=\"elementor elementor-5690\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-0af1a45 elementor-reverse-mobile elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"0af1a45\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-36483bd\" data-id=\"36483bd\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-509cb6d elementor-widget elementor-widget-text-editor\" data-id=\"509cb6d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" class=\"alignleft size-full wp-image-5696\" src=\"https:\/\/sunridgemedical.com\/wp-content\/uploads\/2022\/12\/mixed_connective_tissue-e1648002411890.jpg\" alt=\"mixed connective tissue Disease\" width=\"300\" height=\"199\" \/>Mixed Connective Tissue Disease, or MCTD, is an <a href=\"\/conditions\/autoimmune-diseases\/\">autoimmune disease<\/a> in which the body\u2019s immune system attacks the structural parts of the body which hold the cells together. Primarily, this includes the molecules of elastin and collagen. Those suffering from Mixed Connective Tissue Disease demonstrate symptoms from three separate <a href=\"\/conditions\/autoimmune-diseases-treatment\/\">autoimmune diseases <\/a>\u00a0&#8211; <a href=\"\/conditions\/cancer-fight\/scleroderma\/\">scleroderma<\/a>, <a href=\"\/alternative-lupus-treatment\/\">systemic lupus<\/a>, and erytheatosus. It can occur anytime in life but the average age for on-set is between teenage years and one\u2019s 30\u2019s. 80% of suffers are women. This means MCTD is fifteen times more likely to occur in women as in men; this has caused scientists to hypothesize that the disease is related to hormones.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-831809f elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"831809f\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-2455f5d\" data-id=\"2455f5d\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-48c3952 elementor-widget elementor-widget-heading\" data-id=\"48c3952\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Symptoms of Mixed Connective Tissue Disease<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3850551 elementor-widget elementor-widget-text-editor\" data-id=\"3850551\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Early symptoms of Mixed Connective Tissue Disease are often subtle and therefore disregarded. These can include swollen hands and fingers, rashes, discoloration of the eyelids, hair loss, red patches on knuckles, digestive problems, fatigue, sore throat, and development of allergies. These symptoms can become worse slowly or quite rapidly. Advanced stages of MCTD can come with symptoms including muscle weakness and pain, arthritis, and infections in the gums, stomach, and lungs. Some may develop inflammation in the membrane around the lungs; this can lead to shortness of breath or other more serious symptoms. Some may see a development of <a href=\"\/conditions\/kidney-cancer\/\">kidney disease<\/a> or even <a href=\"\/conditions\/heart-disease\/\">heart disease<\/a>.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-3367e1e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"3367e1e\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-2308c0c\" data-id=\"2308c0c\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-cb010db elementor-widget elementor-widget-heading\" data-id=\"cb010db\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">References on Mixed Connective Tissue Disease<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-76f5a33 elementor-widget elementor-widget-text-editor\" data-id=\"76f5a33\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\tAlves, M. R., &#038; Isenberg, D. A. (2020). \u201cMixed connective tissue disease\u201d: a condition in search of an identity. Clinical and experimental medicine, 20(2), 159\u2013166. <a href=\"https:\/\/link.springer.com\/article\/10.1007\/s10238-020-00606-7\" rel=\"noopener\" target=\"_blank\">https:\/\/doi.org\/10.1007\/s10238-020-00606-7 <\/a>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0fc8fc6 elementor-widget elementor-widget-text-editor\" data-id=\"0fc8fc6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Mixed connective tissue disease was first described as a new <a href=\"\/conditions\/autoimmune-diseases-treatment\/\">autoimmune rheumatic disease<\/a> in 1972 based on the claim of a distinct clinical picture associated with anti-RNP antibody positivity. Subsequently, this new entity has divided opinions in the rheumatology community. We have reviewed recent cohort studies with more than 100 patients, comparing the clinical and immunological features, treatment, prognosis and evolution to well-defined autoimmune rheumatic diseases. We also reviewed clinical features of undifferentiated autoimmune rheumatic diseases based on the most recent studies. After gathering and reviewing these data, we discuss whether the designation \u201cmixed connective tissue disease\u201d should be maintained.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-ea5c330 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"ea5c330\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-913435c\" data-id=\"913435c\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-09ccb2e elementor-widget elementor-widget-text-editor\" data-id=\"09ccb2e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><em>For answers or to make an appointment, call us toll-free at <strong><a href=\"tel: 800-923-7878\">800-923-7878 <\/a><\/strong>to speak with a Patient Care Team.<br \/><\/em>Recover your vitality, reclaim your energy and rediscover your health.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Mixed Connective Tissue Disease, or MCTD, is an autoimmune disease in which the body\u2019s immune system attacks the structural parts of the body which hold the cells together. Primarily, this includes the molecules of elastin and collagen. Those suffering from Mixed Connective Tissue Disease demonstrate symptoms from three separate autoimmune diseases \u00a0&#8211; scleroderma, systemic lupus, [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2012,"parent":2034,"menu_order":13,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-5690","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/sunridgemedical.com\/wp-json\/wp\/v2\/pages\/5690","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sunridgemedical.com\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sunridgemedical.com\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sunridgemedical.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/sunridgemedical.com\/wp-json\/wp\/v2\/comments?post=5690"}],"version-history":[{"count":0,"href":"https:\/\/sunridgemedical.com\/wp-json\/wp\/v2\/pages\/5690\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/sunridgemedical.com\/wp-json\/wp\/v2\/pages\/2034"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/sunridgemedical.com\/wp-json\/wp\/v2\/media\/2012"}],"wp:attachment":[{"href":"https:\/\/sunridgemedical.com\/wp-json\/wp\/v2\/media?parent=5690"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}